In step 4 fructose 1,6-bisphosphate is cleaved by fructose bisphosphate aldolase to form dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (G3P). This reaction is unfavorable written at standard state. Cellularly, the change in free energy is close to zero.
In step 5 DHAP is converted to G3P by triose phosphate isomerase.
Why is DHAP converted to G3P?
The purpose of this reaction is to allow both products of the aldolase reaction to continue in glycolysis.
No comments:
Post a Comment